Eucalyptol (1,8-Cineole)
Respiratory decongestant, antimicrobial, anti-inflammatory, flavoring agent, penetration enhancer
Eucalyptol (1,8-cineole) is a natural bicyclic monoterpene ether that is the principal constituent of eucalyptus oil (60-85% in Eucalyptus globulus). As a purified isolate, eucalyptol is a colorless liquid with a characteristic fresh, camphoraceous, eucalyptus-like odor. It has well-established pharmaceutical applications as a mucolytic and anti-inflammatory agent in respiratory medicines, and has demonstrated clinical efficacy equivalent to oral steroids in certain respiratory conditions. Fresure supplies high-purity eucalyptol (99% min) obtained through fractional distillation of eucalyptus oil under vacuum, with each batch verified by GC analysis. The isolate offers consistent, reproducible performance compared to whole eucalyptus oil, making it the preferred choice for pharmaceutical formulations, standardized flavor preparations, and applications requiring precisely defined active ingredient content.
| Botanical Name | 1,8-Cineole (1,3,3-trimethyl-2-oxabicyclo[2.2.2]octane) |
|---|---|
| Other Names | Cineole, Cajeputol, Eucalyptole, 1,8-Epoxy-p-menthane, An Ye Su |
| Country of Origin | Isolated from eucalyptus oil; primary sources include China, Australia, and South Africa |
| Plant Family | ~ |
| Parts Used | ~ |
| Extraction Method | ~ |
| CAS Number | 470-82-6 |
| Color / Appearance | Colorless, clear, mobile liquid |
| Odor | Characteristic fresh, camphoraceous, slightly spicy eucalyptus-like odor; cooling sensation on inhalation |
| Specific Gravity | 0.921 - 0.925 (20 deg C) |
| Refractive Index | 1.455 - 1.460 (20 deg C) |
| Optical Rotation | -0.5 deg to +0.5 deg (neat, 20 deg C) |
| Flash Point | 48-52 deg C (closed cup) |
| Solubility | Slightly soluble in water (0.35%); miscible with ethanol, ether, chloroform, fixed oils, and most organic solvents |
| Major Constituents | 1,8-Cineole (99% min), traces of limonene, alpha-pinene, para-cymene |
Respiratory decongestant, antimicrobial, anti-inflammatory, flavoring agent, penetration enhancer
1,8-Cineole (99% min), traces of limonene, alpha-pinene, para-cymene
Active pharmaceutical ingredient (API) in cough suppressants, expectorants, chest rubs, inhalants, and nasal decongestants. Demonstrated mucolytic, bronchodilatory, and anti-inflammatory effects in clinical studies. Used as a permeation enhancer in transdermal and topical drug delivery systems. Key ingredient in 'Soledum' and similar proprietary respiratory medications.
GRAS flavoring substance (FEMA GRAS 2465). Used in confectionery (especially cough drops and medicated candies), baked goods, beverages, and chewing gum. The characteristic fresh, cooling flavor provides both taste and functional respiratory benefits.
Flavoring and antimicrobial component in toothpaste, mouthwash, and breath fresheners. Activity against oral pathogens including Streptococcus mutans, Porphyromonas gingivalis, and Candida albicans. Often combined with menthol and thymol for comprehensive oral care formulations.
Used as a bio-based solvent in specialty cleaning products and degreasers. Natural insecticide and acaricide in agricultural and household pest control formulations. Heat transfer fluid additive and flavor component in e-cigarette liquids.
Peppermint, Lavender, Rosemary, Tea Tree, Pine Needle, Lemon, Cajeput, Camphor
Custom packaging and private labeling available upon request.
Store in tightly sealed containers in a cool, dry, well-ventilated area away from ignition sources. Eucalyptol is flammable (flash point ~50 deg C). Protect from heat, sparks, and open flame. Shelf life: 2-3 years under recommended conditions.
Under recommended storage conditions — tightly sealed in a cool, dry environment away from direct sunlight — Eucalyptol (1,8-Cineole) remains stable for 2 to 3 years. Monitor for any changes in aroma, color, or viscosity before use in production batches.
Eucalyptol (1,8-Cineole) is from the . This method preserves the full spectrum of volatile aromatic compounds and bioactive constituents that define the oil''s therapeutic and sensory profile.
Every shipment includes a Certificate of Analysis (COA) detailing the batch-specific chemical profile (GC/MS or GC-FID), physical parameters (specific gravity, refractive index, optical rotation), and organoleptic assessment. Material Safety Data Sheet (MSDS/SDS) is also provided. Additional documentation — including GC/MS chromatograms, pesticide residue analysis, heavy metal testing, and allergen statements — is available upon request.
Standard MOQ is 1 kg for most compound / isolates, with bulk pricing available at 5 kg, 25 kg, and 180 kg drum quantities. Contact our sales team for current pricing and availability for your required volume.
Yes. We provide complimentary 10–30 mL samples of most products for qualified B2B buyers to evaluate quality, aroma, and suitability before placing bulk orders. Sample requests are subject to availability and shipping costs may apply. Request a sample through our contact form.
Contact our team for pricing, samples, and technical documentation. We respond to all B2B inquiries within 24 hours.
