Ursolic Acid (Plant Triterpenoid)
Anti-inflammatory, antitumor, hepatoprotective, antimicrobial, cosmetic anti-aging active
Ursolic acid is a naturally occurring pentacyclic triterpenoid found widely in the plant kingdom, particularly in apple peels, rosemary, oregano, holy basil (Ocimum sanctum), loquat leaves, and the waxy coating of many fruits. This bioactive compound has attracted significant research interest due to its remarkably broad spectrum of pharmacological activities, including anti-inflammatory, antitumor (via multiple mechanisms including apoptosis induction and angiogenesis inhibition), hepatoprotective, and antimicrobial effects. In cosmetics, ursolic acid has gained considerable attention as an anti-aging active ingredient due to its ability to inhibit elastase and collagenase (enzymes that degrade skin structural proteins) and stimulate collagen synthesis. Fresure supplies ursolic acid extracted from loquat leaf (Eriobotrya japonica) and rosemary (Rosmarinus officinalis), available in a range of purities from cost-effective 25% to high-purity 98% pharmaceutical grade.
| Botanical Name | Ursolic acid (3beta-hydroxy-urs-12-en-28-oic acid) |
|---|---|
| Other Names | Ursolic Acid, Malol, Urson, Prunol, Micromerol, Ursolic Acid 25% / 50% / 98%, Xiong Guo Suan |
| Country of Origin | Extracted from loquat leaf (China), rosemary (Mediterranean, China), and apple pomace (global apple processing regions) |
| Plant Family | ~ |
| Parts Used | ~ |
| Extraction Method | ~ |
| CAS Number | 77-52-1 |
| Color / Appearance | 25-50%: Light yellow to brownish fine powder; 90-98%: White to off-white fine crystalline powder |
| Odor | Essentially odorless to faint characteristic plant odor (varies with purity and source plant) |
| Specific Gravity | ~1.1 (solid) |
| Refractive Index | ~ |
| Optical Rotation | +66 deg to +68 deg (1% in pyridine, 20 deg C, 98% purity) |
| Flash Point | Non-flammable solid; degrades above 280 deg C |
| Solubility | Practically insoluble in water; sparingly soluble in ethanol and most organic solvents; soluble in hot ethanol, pyridine, DMSO, and alkalies (forms water-soluble salts); freely soluble in chloroform-methanol mixtures |
| Major Constituents | Ursolic acid (customizable: 25%, 50%, 90%, 98% by specification), oleanolic acid (co-occurring isomer), betulinic acid (trace) |
Anti-inflammatory, antitumor, hepatoprotective, antimicrobial, cosmetic anti-aging active
Ursolic acid (customizable: 25%, 50%, 90%, 98% by specification), oleanolic acid (co-occurring isomer), betulinic acid (trace)
High-value anti-aging active in premium skincare formulations. Clinically demonstrated to inhibit matrix metalloproteinases (MMPs) including collagenase and elastase, preserving skin structural proteins. Stimulates collagen synthesis in dermal fibroblasts. Used in anti-wrinkle serums, eye creams, firming treatments, and anti-aging day/night creams. Often combined with vitamin C, retinol, and peptides for synergistic anti-aging effects.
Preclinical and clinical research has demonstrated: antitumor activity against multiple cancer cell lines (melanoma, leukemia, liver, breast, prostate); hepatoprotective effects; anti-inflammatory activity through COX-2 and NF-kappaB pathway inhibition; and antimicrobial activity against various pathogens including Staphylococcus aureus. Used as a dietary supplement ingredient and pharmaceutical intermediate for ursolic acid-derived drug candidates.
Natural triterpene supplement for muscle health (recent research demonstrated ursolic acid's ability to reduce muscle atrophy and stimulate muscle hypertrophy), metabolic health (AMPK activation, glucose uptake enhancement), and general anti-aging support. Used in sports nutrition and healthy aging supplement formulations.
Standardized reference compound for pharmacological research. Used in drug discovery programs as a lead compound for semi-synthetic derivatives with enhanced bioavailability and target selectivity. Reference standard for QC of herbal medicines containing ursolic acid (loquat leaf, rosemary, holy basil).
Rosemary Extract, Green Tea Extract, Vitamin C, Vitamin E, Hyaluronic Acid, Coenzyme Q10, Retinol
Custom packaging and private labeling available upon request.
Store in tightly sealed containers in a cool, dry place protected from light. Ursolic acid is stable under normal conditions but hygroscopic at high purities; keep desiccated. Shelf life: 2-3 years under recommended conditions.
Under recommended storage conditions — tightly sealed in a cool, dry environment away from direct sunlight — Ursolic Acid remains stable for 2 to 3 years. Monitor for any changes in aroma, color, or viscosity before use in production batches.
Ursolic Acid is from the . This method preserves the full spectrum of volatile aromatic compounds and bioactive constituents that define the oil''s therapeutic and sensory profile.
Every shipment includes a Certificate of Analysis (COA) detailing the batch-specific chemical profile (GC/MS or GC-FID), physical parameters (specific gravity, refractive index, optical rotation), and organoleptic assessment. Material Safety Data Sheet (MSDS/SDS) is also provided. Additional documentation — including GC/MS chromatograms, pesticide residue analysis, heavy metal testing, and allergen statements — is available upon request.
Standard MOQ is 1 kg for most compound / isolates, with bulk pricing available at 5 kg, 25 kg, and 180 kg drum quantities. Contact our sales team for current pricing and availability for your required volume.
Yes. We provide complimentary 10–30 mL samples of most products for qualified B2B buyers to evaluate quality, aroma, and suitability before placing bulk orders. Sample requests are subject to availability and shipping costs may apply. Request a sample through our contact form.
Contact our team for pricing, samples, and technical documentation. We respond to all B2B inquiries within 24 hours.
